Hepatic toxicology following single and multiple exposure of engineered nanomaterials utilising a novel primary human 3D liver microtissue model

Table 1 Main physical and chemical properties of tested NMs (adapted and reproduced from 24)

NM code	NM type	Phase	XRD size [nm]	TEM size	Surface area (BET)[m²/g]	Known coating	Size in human liver maintenance medium (Nanosight)^Ψ	Dissolution in medium (%)
NM 110	ZnO	Zincite	70 to >100	20-250/50-350	14	None	130 ± 48 (64%)	23.36-46.70%
NM 110	ZnO	Zincite	70 to >100	20-250/50-350	14	None	242 ± 32 (25%)	23.36-46.70%
NM 300	Ag	Ag	7^$	8-47 (av. 17.5)	NA	PVP capped	98 ± 43	<1%
			14^£
			<18
NM 400	MWCNT	-	-	D: 5-35	298	None	NA	NA
NM 400	MWCNT	-	-	L: 700-3000	298	None	NA	NA
NRCWE 002	TiO₂	Rutile	10	80-400	84	Triethylpropylaminosaline	278 ± 151	NA

ISSN: 1743-8977