Figure 4From: Effect of wood smoke exposure on vascular function and thrombus formation in healthy fire fightersEffect of wood smoke and filtered air on platelet activation, fibrinolysis and thrombus formation ex vivo. (a) Platelet-monocyte binding and (b) platelet expression of P-selectin were unchanged 2 and 24 hours following exposure to wood smoke or filtered air (ANOVA with repeated measures, P > 0.05, n = 11–16). (c) Bradykinin caused a dose-dependent release of tissue-plasminogen activator (t-PA) antigen (2-way ANOVA with repeated measures, P < 0.01), which was similar after both exposures (P > 0.05, n = 16). (d) Thrombus formation under high-sheer conditions in the Badimon chamber was similar 2 hours after exposure to wood smoke or filtered air (Student’s t-test, P > 0.05, n = 13). All data expressed as mean ± SEM.Back to article page