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Figure 4 | Particle and Fibre Toxicology

Figure 4

From: Effect of wood smoke exposure on vascular function and thrombus formation in healthy fire fighters

Figure 4

Effect of wood smoke and filtered air on platelet activation, fibrinolysis and thrombus formation ex vivo. (a) Platelet-monocyte binding and (b) platelet expression of P-selectin were unchanged 2 and 24 hours following exposure to wood smoke or filtered air (ANOVA with repeated measures, P > 0.05, n = 11–16). (c) Bradykinin caused a dose-dependent release of tissue-plasminogen activator (t-PA) antigen (2-way ANOVA with repeated measures, P < 0.01), which was similar after both exposures (P > 0.05, n = 16). (d) Thrombus formation under high-sheer conditions in the Badimon chamber was similar 2 hours after exposure to wood smoke or filtered air (Student’s t-test, P > 0.05, n = 13). All data expressed as mean ± SEM.

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