Figure 2

Uptake of: ( 1) Ag ENMs 50 nm: ( A) in cytoplasmic vesicle after 2 h exposure; ( B) in close proximity to chromosomes/ chromatin in mitotic cells after 24 h exposure , (C) outside the cell/ associated with cellular debris ( 48 h exposure ); (2) Ag ENMs 80 nm: ( A) in cytoplasmic vesicle after 24 h exposure, ( B) in lysosomes after 48 h exposure; ( C) in nucleus after 48 h; ( 3 ) Ag ENMs 200 nm ( A) in cytoplasmic vesicles after 2 h exposure; ( B) in lysosomes after 24 h exposure, ( C) in vesicles localised close to the nuclear membrane ( after 24 h exposure).