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Table 2 Number of animals per exposure group, duration, and biological assessments

From: Metal rich particulate matter impairs acetylcholine-mediated vasorelaxation of microvessels in mice

Exposure time N PM sample PM nominal concentration Collected tissues/biological fluids Biological assessment
1x 6 JC 0.5 μg BALF BALF evaluation of cell differentials, counts, and protein concentration
1x ZH
1x ZH + NiSO4
1x ZH + CuSO4
1x ZH + AsO3
1x ZH + SeCl4
1x 4 NiSO4 + H2O
1x NiSO4 + Carbon
1x 8 JC 0.25 μg BALF, Blood BALF evaluation of cell differentials, counts, and protein, various inflammation and vascular dysfunction, vessel function
3 wks 14 BALF, Blood, Mesenteric Artery
2x/wk
1x 8 ZH BALF, Blood
3 wks 8 BALF, Blood, Mesenteric Artery
2x/wk
1x 8 ZH + NiSO4 BALF, Blood
3 wks 16 BALF, Blood, Mesenteric Artery
2x/wk
  1. H2O controls were matched to each exposure group.