Fig. 8

TEM images of intracellular particles in the A549 CML. (a) Agglomerates, (b, c) small agglomerates and (d) single particles in the cytoplasm and (e) particles next to the cell nucleus 24 h after exposure to 100 ng/cm2 18 nm AuNP in the ALICE system. In (b) and (c) the surface of the monolayer (top left) and the PET membrane on which the CML were grown (bottom right) can be seen. The arrows are pointing towards the particles. (e: without lead citrate and uranyl acetate staining)