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Fig. 1 | Particle and Fibre Toxicology

Fig. 1

From: Acute and subchronic exposure to air particulate matter induces expression of angiotensin and bradykinin-related genes in the lungs and heart: Angiotensin-II type-I receptor as a molecular target of particulate matter exposure

Fig. 1

Particulate matter induces lung AT1R and ACE mRNA in a size- and time-dependent manner. The animals were exposed to coarse (CP), fine (CP) and ultrafine particulate (UFP). A control group was exposed to filtered air (FA). The semi-quantitative levels of Angiotensin Receptor Type-1 (At1r) and Angiotensin-I Converting Enzyme (Ace) mRNA after acute (3 days, 5 h/d) and subchronic (8 weeks, 5 h/d, 4 d/week) exposure are shown. Scatter dot plot shows the value of the median. Below each graph representatives gels illustrating the expression levels of mRNA are shown. * indicates significant differences among groups (n = 4 per group, p < 0.05)

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