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Fig. 4 | Particle and Fibre Toxicology

Fig. 4

From: Acute and subchronic exposure to air particulate matter induces expression of angiotensin and bradykinin-related genes in the lungs and heart: Angiotensin-II type-I receptor as a molecular target of particulate matter exposure

Fig. 4

Particle matter modifies the AT1R subcellular distribution in lung tissue in a time-dependent manner. Representative gels of Angiotensin-II type-I receptor (AT1R) detection in lung nuclear and non-nuclear fractions after acute (upper panel) and subchronic (lower panel) exposure to coarse particulate (CP), fine particulate (FP), ultrafine particulate (UFP) or filtered air (AF). We used GAPDH and acetylated Histone-4 (H4ac) as cytosolic and nuclear quality control targets, respectively, and actin was used as a general protein loading control. Representative blot of n = 4

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