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Fig. 8 | Particle and Fibre Toxicology

Fig. 8

From: Acute and subchronic exposure to air particulate matter induces expression of angiotensin and bradykinin-related genes in the lungs and heart: Angiotensin-II type-I receptor as a molecular target of particulate matter exposure

Fig. 8

Subchronic PM exposure increases intramyocardial coronary artery wall thickness independently of PM size. Hematoxylin & Eosin staining of 5 μm myocardial slices. a) Representative slides of the hearts from rats exposed to Filtered Air (FA), coarse (CP), fine (FP) and ultrafine (UFP) particulates for 5 h/day, 4 days/week for 8 weeks. b) Box plot of ten random measurements of each coronary artery wall measured in the tissues. c) Semi-quantitative analysis of the presence of mononuclear cells in heart coronary arteries in the groups exposed to FP and UFP. L: Artery lumen; A: Tunica adventitia; I-M: Tunica intima-media. Yellow arrows indicate mononuclear cells and blue arrows indicate a blood vessel. Scatter dot plot shows the value of the median. * indicates significant differences among groups (n = 4 per group, p < 0.05)

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Particle and Fibre Toxicology

ISSN: 1743-8977

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