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Fig. 6 | Particle and Fibre Toxicology

Fig. 6

From: Cutaneous exposure to agglomerates of silica nanoparticles and allergen results in IgE-biased immune response and increased sensitivity to anaphylaxis in mice

Fig. 6

Prevention of Dp + nSP30-mediated IgE-biased immune response by surface modification of nSP30. ac Plasma levels of Dp-specific (a) IgE, (b) IgG, and (c) IgG1 and IgG2a at 24 h after final treatment of NC/Nga mice with Dp alone, Dp + nSP30, or Dp + nSP30C, as analyzed by ELISA. Data are given as means ± SEMs (n = 5). *P < 0.05, **P < 0.01 vs. Dp-alone group

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