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Fig. 7 | Particle and Fibre Toxicology

Fig. 7

From: Cutaneous exposure to agglomerates of silica nanoparticles and allergen results in IgE-biased immune response and increased sensitivity to anaphylaxis in mice

Fig. 7

Effect of topical application of dispersed mixture of Dp + nSP30 on antibody response. a–c Plasma levels of Dp-specific (a) IgE, (b) IgG, and (c) IgG1 and IgG2a at 24 h after final topical treatment of NC/Nga mice with Dp alone or Dp + nSP30 in water, as analyzed by ELISA. Data are given as means ± SEMs (n = 5 or 6). *P < 0.05, **P < 0.01 vs. Dp-alone group

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