Test groups
|
Concentration / dose level
|
PCEs with micronuclei (%)
|
Rangea
|
PCE per 2000 erythrocytes
|
---|
(n = 5/group)
|
(mg/m3)
| | | |
MALE
|
Air control
|
0
|
0.340
|
2 - 17
|
1099
|
Graphistrength© C100
|
0.05
|
0.440
|
5 - 11
|
1073
|
0.25
|
0.280
|
2 - 10
|
1094
|
5.00
|
0.210
|
3 - 8
|
1081
|
Positive controlb
|
20
|
0.833*
|
10 - 26
|
806
|
FEMALE
|
Vehicle
|
0
|
0.290
|
3 - 9
|
1155
|
Graphistrength© C100
|
0.05
|
0.210
|
1 - 8
|
1223
|
0.25
|
0.190
|
1 - 5
|
1147
|
5.00
|
0.220
|
2 - 9
|
1091
|
Positive controlb
|
20
|
0.750**
|
8 - 28
|
813
|
- */**: Non-parametric Mann-Whitney test significant <0.05 (*) or <0.01 (**)
-
aper 2000 PCEs per animal
-
bCPA, 20 mg/kg bw