|
Test groups (n = 5/group)
|
hOGG1
|
Air control
|
Graphistrength© C100 (mg/m3)
|
Positive controla
|
|---|
| | |
0
|
0.05
|
0.25
|
5.0
| |
|---|
|
LUNG
|
|
% of DNA in tailb
|
-
|
8.8 ± 5.5
|
3.4 ± 1.5*
|
8.2 ± 5.1
|
4.7 ± 3.7
|
48.7 ± 3.0**
|
|
+
|
20.2 ± 5.2
|
16.7 ± 5.7
|
22.3 ± 11.8
|
17.9 ± 5.9
|
79.1 ± 7.9**
|
|
Relative ratio of ghost cellc
|
-
|
-
|
1.0
|
1.2
|
0.8
|
0.6**
|
|
+
|
-
|
2.1**
|
2.0**
|
1.3
|
1.1
|
|
KIDNEYS
|
|
% of DNA in tailb
|
-
|
7.4 ± 4.4
|
7.5 ± 4.2
|
8.2 ± 4.2
|
9.7 ± 3.1
|
72.5 ± 5.8**
|
|
+
|
22.8 ± 7.4
|
22.4 ± 7.3
|
23.4 ± 8.4
|
24.3 ± 8.0
|
74.0 ± 5.9**
|
|
Relative ratio of ghost cellc
|
-
|
-
|
1.6
|
0.9
|
1.5
|
2.8**
|
|
+
|
-
|
1.1
|
1.6*
|
1.7**
|
0.6*
|
|
LIVER
|
|
% of DNA in tailb
|
-
|
3.8 ± 3.1
|
3.4 ± 1.6
|
1.8 ± 1.0
|
5.5 ± 2.9
|
71.2 ± 9.1**
|
|
+
|
11.6 ± 6.4
|
7.5 ± 1.5
|
7.7 ± 1.1
|
9.6 ± 3.0
|
78.6 ± 3.7**
|
|
Relative ratio of ghost cellc
|
-
|
-
|
0.2
|
0.5
|
2.8**
|
4.9**
|
|
+
|
-
|
0.5*
|
0.2**
|
1.1
|
1.7**
|
- */**/***: Non-parametric Mann-Whitney test significant <0.05 (*), <0.01 (**)
-
aMMS
-
bMean of median ± sd
-
cMean value in treated groups/mean control value
