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Table 3 Histopathology scores of exposed and control pregnant and non-pregnant groups immediately after delivery on GD 19 (PND 0) and 50 days later (PND 50)

From: Effects of prenatal inhalation exposure to copper nanoparticles on murine dams and offspring

Experimental Group Number of mice per group Histopathology Scorea
Alveolar macrophages Alveolar debris Perivascular cuffingb
Exposed Pregnant, PND 0 n = 4 1 2 0.75
Non-Pregnant, PND 0 n = 5 1 1 1.8
Pregnant, PND 50 n = 5 1 0 0.2
Non-Pregnant, PND 50 n = 5 0.6 0 0.2
Shams Pregnant, PND 0 n = 4c 0 0 0
Non-Pregnant, PND 0 n = 4c 0 0 0
  1. PND postnatal day
  2. aScoring system: 0 = none, 1 = few/rare, 2 = multifocal/moderate, 3 = many/coalescing and/or diffuse
  3. bLymphocytes and plasma cells surrounding blood vessels
  4. cOnly 4 mice out of 5 were evaluated for pathology changes in control groups