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Fig. 2 | Particle and Fibre Toxicology

Fig. 2

From: Silica coating influences the corona and biokinetics of cerium oxide nanoparticles

Fig. 2

Bronchoalveolar lavage analysis after IT instillation of uncoated or silica-coated CeO2 NPs. a Dose-dependent increases in lavaged neutrophils and b lactate dehydrogenase levels in BAL at 24 h post-instillation. c Lavaged macrophages increased with uncoated but decreased with silica-coated CeO2 at the highest NP dose. d Lavaged neutrophils and e lactate dehydrogenase, MPO and albumin (data not shown) returned to normal levels but f macrophage recruitment was observed at 5 days post-instillation of 1 mg/kg CeO2. (* increased, # decreased, P < 0.05, MANOVA. Data are mean ± SEM, n = 5/group)

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