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Fig. 5 | Particle and Fibre Toxicology

Fig. 5

From: Silica coating influences the corona and biokinetics of cerium oxide nanoparticles

Fig. 5

Analysis of nanoparticles after incubation with BAL fluid. a NP-bound rat BAL proteins were analyzed by 1D gel electrophoresis and Mass Spectrometry. The molecular weights (kDa) of reference proteins are shown in lane MW. Five proteins identified by LC-MS are indicated on right. b LC-MS profiles of the same five proteins show the influence of silica coating on the protein corona profile. c Compartmental distribution of neutron activated uncoated and silica-coated CeO2 at 24 h post-instillation. No significant differences in distribution were observed between the two CeO2 NPs. Data are mean ± SEM, n = 5/group

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