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Table 3 Cerium concentration in different tissues at 7 days after gavage administration of uncoated or silica-coated CeO2 NPs

From: Silica coating influences the corona and biokinetics of cerium oxide nanoparticles

  CeO2 Silica-coated CeO2
  ng/g ± SE ng/g ± SE
Lungs 0.27 ± 0.16 0.07 ± 0.03
Liver 0.11 ± 0.04 0.07 ± 0.03
Bone 0.55 ± 0.31 0.06 ± 0.06
Cecum 0.22 ± 0.08 0.18 ± 0.13
Large intestine 0.76 ± 0.72 0.20 ± 0.15
Bone marrow 0.00 ± 0.00 0.25 ± 0.25
Spleen 0.06 ± 0.06 0.15 ± 0.15
Stomach 0.31 ± 0.18 2.64 ± 1.84
Kidneys 0.13 ± 0.13 0.09 ± 0.04
Small intestine 0.12 ± 0.05 0.39 ± 0.27
Heart 0.34 ± 0.21 0.35 ± 0.21
Testes 0.04 ± 0.04 0.09 ± 0.04
Skeletal muscle 0.06 ± 0.05 0.01 ± 0.01
Brain 0.05 ± 0.05 0.00 ± 0.00
Skin 0.04 ± 0.04 0.04 ± 0.02
Plasma 0.04 ± 0.04 0.03 ± 0.03
RBC 0.00 ± 0.00 0.03 ± 0.03
  1. Data are mean ± SE ng/g cerium concentration, n = 5/group
  2. Ce concentration was estimated (ng/μCiNPs x μCi/gtissue)
  3. No significant difference was observed between the two group