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Fig. 6 | Particle and Fibre Toxicology

Fig. 6

From: Nanoparticle-allergen interactions mediate human allergic responses: protein corona characterization and cellular responses

Fig. 6

Determination of protease activity of free Der p 1 versus AuNP-Der p 1 conjugates. a Enzymatic activity assay of 30 ng AuNP-Der p 1 conjugates compared to 50 and 100 ng free Der p 1. b Stability of conjugates addressed by enzymatic activity of 30 ng AuNP-Der p 1 conjugates upon storage at 4 °C. In conjugates the given values refer to amount of coupled allergen. c TEER measurements of A549 cells to monitor the formation of a tight cell layer. d TEER measurements of A549 cells exposed to controls, free Der p 1 and AuNP-Der p 1 conjugates (*, p < 0.05). e Permeation of Fluorescein through a tight monolayer of A549 cells exposed to controls, free Der p 1 and AuNP-Der p 1 conjugates (*, p < 0.05)

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Particle and Fibre Toxicology

ISSN: 1743-8977

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