From: Persistent effects of Libby amphibole and amosite asbestos following subchronic inhalation in rats
Air control | AM | LA | LA | LA | |
---|---|---|---|---|---|
Target mass concentration (mg/m3) | 0.00 | 3.50 | 0.50 | 3.50 | 25.00 |
Actual mass concentration (mg/m3) | 0.08 ± 0.18 | 3.67 ± 1.58 | 0.53 ± 0.11 | 3.59 ± 0.91 | 26.76 ± 9.11 |
Foreign Bodya | 0 | 6* | 2 | 6* | 7* |
Alveolus Inflammationb | 0 | 7 (1.0)* | 6 (0.9)* | 7 (2.0)* | 7 (2.0)* |
Focal Chronic Inflammationc | 3 (0.4) | 3 (0.4) | 5 (0.7) | 1 (0.1) | 0 |
Bronchiole Epithelial Hyperplasia | 0 | 0 | 0 | 0 | 5 (0.7)* |
Interstitial Fibrosisd | 0 | 4 (0.6) | 0 | 3 (0.4) | 7 (1.0)* |