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Fig. 4 | Particle and Fibre Toxicology

Fig. 4

From: Ultrasmall superparamagnetic iron oxide nanoparticles acutely promote thrombosis and cardiac oxidative stress and DNA damage in mice

Fig. 4

Direct in vitro effect after the administration of ultrasmall superparamagnetic iron oxide nanoparticles (USPIO), diesel exhaust particles (DEP) or saline (control) on platelet aggregation in whole blood of untreated mice. Platelet aggregation in untreated whole blood 3 min after the addition of either saline or USPIO was assessed. The degree of platelet aggregation following USPIO exposure was expressed as a percent of control (saline-treated blood). Data are mean ± SEM (n = 4). *P < 0.001 compared with saline-treated blood within the same group

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