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Fig. 9 | Particle and Fibre Toxicology

Fig. 9

From: Multi-walled carbon nanotubes directly induce epithelial-mesenchymal transition in human bronchial epithelial cells via the TGF-β-mediated Akt/GSK-3β/SNAIL-1 signalling pathway

Fig. 9

Representative immunoistochemical images of E-cadherin and vimentin in lungs. Representative immunoistochemical images of E-cadherin and vimentin in lung sections from mice exposed at 30 days to MWCNTs through pharyngeal aspiration. E-cadherin was mainly expressed in type II pneumocytes in both control and MWCNT exposed lungs. The number of E-cadherin positive cells in NP-exposed compared to control sections was decreased (a, c, e), while the expression for vimentin was increased (b, d, f) (20×; scale bar = 60 μm)

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