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Fig. 9 | Particle and Fibre Toxicology

Fig. 9

From: Atomic layer deposition coating of carbon nanotubes with zinc oxide causes acute phase immune responses in human monocytes in vitro and in mice after pulmonary exposure

Fig. 9

Systemic effects of Z-MWCNT exposure. a Expression of IL-6 in the heart is elevated significantly one day after lung exposure to Z-MWCNT. b IL-6 is slightly elevated in the spleen one day after Z-MWCNT exposure. c Z-MWCNT exposure caused significantly elevated IL-6 in the liver as compared to control and U-MWCNT dosed mice at one day. The number of animals per group at day one was: Control (3), U-MWCNT (4), and Z-MWCNT (4) and at 28 days was: Control (4), U-MWCNT (5), Z-MWCNT (3) . Significance is represented as * as compared to the control and # as compared to U-MWCNT, * denotes P < 0.05, ** denotes P < 0.01, and *** denotes P < 0.001

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