Table 3 Exposure days: Median concentrations of oxidative stress biomarkers in EBC, plasma and creatinine corrected urine (respective unit/g creatinine), presented by time point

Total Reducing Capacity [a.u.]

T1

26 (15–31.5)

162.2 (120–197.3)^a

1555.4 (789.2–3311.7)

T2

27 (13–56.7)

161.8 (107.7–210.3)^a

2082.1 (1061.2–3388.7)

T3

26.2 (15.7–34)

167.3 (116.5–245.3)^a

2118.7 (987.7–4201.8)

T4

26.6 (15–55)

173.5 (99.5–233.7)^a

2355.0 (1351.8–3843.8)

H₂O₂ [μM]

T1

0.08 (˂LOD- 0.3)

4.6 (1.8–11.7)

12.5 (5.3–209.9)

T2

0.07 (˂LOD- 0.6)

4.4 (2.1–10.8)

19.9 (5.8–104.3)

T3

0.05 (˂LOD-0.2)

4.4 (2.0–11.6)

19.5 (5.7–129.9)

T4

0.07 (˂LOD-0.3)

4.4 (2.0–15.7)

39.9 (6.4–135.8)

MDA [nM]

T1

3.8 (˂LOD-30.0)

103.6 (53.7–212.0)

280.2 (151.5–1012.5)

T2

6.4 (˂LOD-18.3)

97.7 (64.1–282.2)

288.3 (126.9–634.3)

T3

5.0 (˂LOD-34.9)

94.5 (71.6–476.6)

272.7 (108.1–513.9)

T4

3.2 (˂LOD-16.8)

108.0 (63.6–529.6)

236.8 (103.6–415.9)

8-OHdG [μg/l]

T1

–

3.8 (˂LOD -15.2)

1.7 (˂LOD -4.8)

T2

–

3.9 (˂LOD -26.7)

1.5 (˂LOD -3.1)

T3

–

4.2 (˂LOD -34.2)

1.8 (˂LOD -19.5)

T4

–

4.5 (˂LOD -39.2)

2.1 (˂LOD -33.1)