Fig. 2From: No involvement of alveolar macrophages in the initiation of carbon nanoparticle induced acute lung inflammation in miceTime course of CNP agglomerate uptake. The amount of by BAL recovered cells showing inclusions of CNP agglomerates was quantified by the examination of cytospins from mice 3 to 24 h after particle instillation. Particle uptake was exclusively observed for macrophages but and no agglomerates we observed in polymorphonuclear, neutrophilic granulocytes (a). Free, not cell-associated particle agglomerates are predominantly detected at the early time points, till 12 h after exposure. Figure 2b shows the time course of the particle uptake given as the percentage of particle laden macrophagesBack to article page