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Fig. 5 | Particle and Fibre Toxicology

Fig. 5

From: No involvement of alveolar macrophages in the initiation of carbon nanoparticle induced acute lung inflammation in mice

Fig. 5

No effect of CNP IT on pro-inflammatory activation status of alveolar macrophages: Alveolar macrophages were isolated by BAL from mice 12 h after water (sham) or 6 and 12 h after CNP IT. Gene expression of the macrophage activation markers Nos2, Tnf and Il1b (a), the chemokines Cxcl1, Cxcl2 and Cxcl5 (b) and the NF- kB signaling pathway genes Nfkbia, Nfkbib and Nfkbiz (c) are presented relative to Actb + Hprt. Values are given as mean ± SEM, n = 4–5. (n.d.: not detected)

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