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Fig. 9 | Particle and Fibre Toxicology

Fig. 9

From: Evaluation of pulmonary and systemic toxicity following lung exposure to graphite nanoplates: a member of the graphene-based nanomaterial family

Fig. 9

Gene Expression in Lung Tissue. Realtive mRNA expression of IL-6 (Il6), MIP-2 (Cxcl2), MCP-1 (Ccl2), MDC (Ccl22), and osteopontin (Spp1) relative to DM control at all time points post-exposure, with the exception of Spp1 which was not measured at 4 h post-exposure. Low dose groups were not evaluated at 1 and 2 months post-exposure. *significantly different from all groups; # significantly different from DM only; ^ significantly different from DM, Gr20-Low, Gr5-Low, and Gr1-Low; p < 0.05

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