Skip to main content

Table 3 Fetal metabolism at 28 dpc for the first generation

From: Maternal exposure to diluted diesel engine exhaust alters placental function and induces intergenerational effects in rabbits

Variable

Number of fetuses

Median [Q1; Q3]

Fully adjusted linear model

C

E

C

E

β value

CI

P-value

Glycemia (mmol/L)

16

20

4.250 [3.200; 4.675]

4.210 [3.150; 5.358]

0.401

[−0.794;1.597]

0.521

Insulin (mUI/L)

17

19

1.800 [1.300; 2.950]

1.000 [0.700; 1.400]

−0.998

[−1.886;-0.111]

0.050*

Total cholesterol (mmol/L)

17

20

1.950 [1.640; 2.620]

2.115 [1.818; 2.455]

0.013

[−0.436;0.462]

0.956

HDL cholesterol (mmol/L)

17

20

0.460 [0.433; 0.498]

0.400 [0.360; 0.490]

0.035

[−0.03;0.099]

0.309

Non-HDL cholesterol (mmol/L)

17

20

1.590 [1.275; 2.165]

1.645 [1.388; 1.948]

−0.022

[−0.412;0.369]

0.915

Triglycerids (mmol/L)

15

20

0.570 [0.460; 0.670]

0.585 [0.445; 0.870]

0.062

[−0.238;0.362]

0.689

ASAT (UI/L)

17

20

168.0 [86.50; 184.5]

171.5 [129.3; 217.5]

26.413

[−19.769;72.594]

0.284

ALAT (UI/L)

10

16

7.000 [6.000; 9.500]

9.000 [7.000; 9.750]

1.18

[−1.068;3.428]

0.326

Creatinine (μmol/L)

17

20

87.00 [84.50; 91.00]

95.00 [92.00; 104.8]

7.329

[−3.003;17.662]

0.190

Urea (mmol/L)

17

20

5.600 [5.150; 5.850]

6.500 [5.425; 7.450]

0.841

[−0.369;2.05]

0.199

IGF-1 (nmol/L)

20

20

1.184 [0.337; 2.368]

0.108 [0.000; 1.581]

−0.105

[−0.179;-0.031]

0.019*

  1. Effect of exposure to engine diesel exhaust on first-generation fetuses was estimated using a linear model with random effect of dam adjusted for litter size and position of the fetus in the horn. All data are expressed as median [Q1; Q3] (*p < 0.05, **p < 0.01, compared with control group)
  2. ASAT ASpartate Amino Transferase, ALAT ALanine Amino Transferase