J774A.1 vs. A549 cells | Cytotoxicity | Cytokine induction |
---|
βV
| βR
| βI-V
| βI-V LO
| βI-V HI
|
---|
R |
0.741
|
0.729
| 0.020 | −0.089 | −0.108 |
p (2-tailed) |
0.035
|
0.040
|
0.963
|
0.835
|
0.800
|
- Consensus cytotoxic potency βV is calculated from in vitro assays conducted in individual cell lines
- Biological reactivity of the particles βR represent absolute values of cytotoxic potency
- Consensus inflammatory potency βI-V represents the average unbiased particle potency response for inducing a cytokine response, where LO and HI are the lower and upper estimates of the index based on the pro- and anti-inflammatory effects of some cytokines
- Numbers in bold represent statistically significant correlations (p ≤ 0.05)