Table 6 Rank order correlations for the combined in vitro (cell lines) and in vivo (BALB/c mouse) particle potency estimates for all particles (PM) and excluding cristobalite (CRI)

Toxicity

 β_{R CELLS} vs. β_{T BALB/c}

CRI

5

-

3

-

DWR1

4

(4)

5

(4)

EHC-2000

2

(2)

2

(2)

0.667

0.109

1.000

<0.001

SRM-1649

1

(1)

1

(1)

TiO₂

3

(3)

4

(3)

Inflammation

 β_{I-V CELLS} vs. β_{I BALB/c}

CRI

4

-

3

-

DWR1

5

(4)

5

(4)

EHC-2000

1

(1)

2

(2)

0.800

0.052

0.800

0.100

SRM-1649

2

(2)

1

(1)

TiO₂

3

(3)

4

(3)

Integrated Potency

 Iβ _CELLS vs. Iβ _BALB/c

CRI

4

-

3

-

DWR1

5

(4)

5

(4)

EHC-2000

1

(1)

2

(2)

0.800

0.052

0.800

0.100

SRM-1649

2

(2)

1

(1)

TiO₂

3

(3)

4

(3)