Table 5 Calculated vascular stress values for coronary arteries and aortic rings
Treatment Group | Coronary Artery | Aorta | ||||
|---|---|---|---|---|---|---|
Maximal Stress Generation (mN/mm2) | Remaining Stress (mN/mm2) | Maximal Stress Generation (mN/mm2) | Remaining Stress (mN/mm2) | |||
| Â | 5-HT | ACh | SNP | 5-HT | ACh | SNP |
 Naive | 4.0 ± 0.5 | 0.1 ± 0.1 | 0.0 ± 0.1 | 4.0 ± 0.5 | 0.1 ± 0.1 | 0.0 ± 0.1 |
1 Day Post IT Exposure | ||||||
 Citrate | 3.5 ± 0.4 | 1.2 ± 0.9 | 0.0 ± 0.1 | 3.5 ± 0.4 | 1.2 ± 0.9 | 0.0 ± 0.1 |
 20 nm AgNP | 4.3 ± 0.5 | 0.3 ± 0.2 | 0.0 ± 0.1 | 4.3 ± 0.5 | 0.3 ± 0.2 | 0.0 ± 0.1 |
 110 nm AgNP | 3.2 ± 0.4 | 0.8 ± 0.5 | 0.0 ± 0.1 | 3.2 ± 0.4 | 0.8 ± 0.5 | 0.0 ± 0.1 |
 PVP | 3.4 ± 0.3 | 0.4 ± 0.3 | 0.1 ± 0.1 | 3.4 ± 0.3 | 0.4 ± 0.3 | 0.1 ± 0.1 |
 20 nm AgNP | 2.7 ± 0.4 | 0.3 ± 0.2 | 0.0 ± 0.1 | 2.7 ± 0.4 | 0.3 ± 0.2 | 0.0 ± 0.1 |
 110 nm AgNP | 3.0 ± 0.5 | 0.4 ± 0.1 | 0.0 ± 0.1 | 3.0 ± 0.5 | 0.4 ± 0.1 | 0.0 ± 0.1 |
7 Day Post IT Exposure | ||||||
 Citrate | 2.4 ± 0.9 | 0.4 ± 0.4 | −0.1 ± 0.1 | 2.4 ± 0.9 | 0.0 ± 0.1 | 0.6 ± 0.2 |
 20 nm AgNP | 3.6 ± 0.4 | −0.1 ± 0.4 | 0.1 ± 0.5 | 3.6 ± 0.4 | 0.3 ± 0.1 | 0.4 ± 0.2 |
 110 nm AgNP | 2.8 ± 0.8 | 0.1 ± 0.1 | −0.2 ± 0.1 | 2.8 ± 0.8 | 0.3 ± 0.3 | 0.0 ± 0.1 |
 PVP | 1.7 ± 0.7 | 0.1 ± 0.0 | −0.3 ± 0.1 | 1.7 ± 0.7 | 0.5 ± 0.4 | 0.5 ± 0.2 |
 20 nm AgNP | 1.6 ± 0.5 | 0.6 ± 0.5 | −0.4 ± 0.1 | 1.6 ± 0.5 | 0.6 ± 0.6 | 0.4 ± 0.1 |
 110 nm AgNP | 3.0 ± 0.6 | 0.1 ± 0.2 | −0.1 ± 0.2 | 3.0 ± 0.6 | 0.5 ± 0.3 | 0.2 ± 0.3 |