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Table 5 Calculated vascular stress values for coronary arteries and aortic rings

From: Impact of pulmonary exposure to gold core silver nanoparticles of different size and capping agents on cardiovascular injury

Treatment Group Coronary Artery Aorta
Maximal Stress Generation (mN/mm2) Remaining Stress (mN/mm2) Maximal Stress Generation (mN/mm2) Remaining Stress (mN/mm2)
  5-HT ACh SNP 5-HT ACh SNP
 Naive 4.0 ± 0.5 0.1 ± 0.1 0.0 ± 0.1 4.0 ± 0.5 0.1 ± 0.1 0.0 ± 0.1
1 Day Post IT Exposure
 Citrate 3.5 ± 0.4 1.2 ± 0.9 0.0 ± 0.1 3.5 ± 0.4 1.2 ± 0.9 0.0 ± 0.1
 20 nm AgNP 4.3 ± 0.5 0.3 ± 0.2 0.0 ± 0.1 4.3 ± 0.5 0.3 ± 0.2 0.0 ± 0.1
 110 nm AgNP 3.2 ± 0.4 0.8 ± 0.5 0.0 ± 0.1 3.2 ± 0.4 0.8 ± 0.5 0.0 ± 0.1
 PVP 3.4 ± 0.3 0.4 ± 0.3 0.1 ± 0.1 3.4 ± 0.3 0.4 ± 0.3 0.1 ± 0.1
 20 nm AgNP 2.7 ± 0.4 0.3 ± 0.2 0.0 ± 0.1 2.7 ± 0.4 0.3 ± 0.2 0.0 ± 0.1
 110 nm AgNP 3.0 ± 0.5 0.4 ± 0.1 0.0 ± 0.1 3.0 ± 0.5 0.4 ± 0.1 0.0 ± 0.1
7 Day Post IT Exposure
 Citrate 2.4 ± 0.9 0.4 ± 0.4 −0.1 ± 0.1 2.4 ± 0.9 0.0 ± 0.1 0.6 ± 0.2
 20 nm AgNP 3.6 ± 0.4 −0.1 ± 0.4 0.1 ± 0.5 3.6 ± 0.4 0.3 ± 0.1 0.4 ± 0.2
 110 nm AgNP 2.8 ± 0.8 0.1 ± 0.1 −0.2 ± 0.1 2.8 ± 0.8 0.3 ± 0.3 0.0 ± 0.1
 PVP 1.7 ± 0.7 0.1 ± 0.0 −0.3 ± 0.1 1.7 ± 0.7 0.5 ± 0.4 0.5 ± 0.2
 20 nm AgNP 1.6 ± 0.5 0.6 ± 0.5 −0.4 ± 0.1 1.6 ± 0.5 0.6 ± 0.6 0.4 ± 0.1
 110 nm AgNP 3.0 ± 0.6 0.1 ± 0.2 −0.1 ± 0.2 3.0 ± 0.6 0.5 ± 0.3 0.2 ± 0.3
  1. The calculated mean maximum stress generated to serotonin (5-HT) or phenylephrine (PE) in coronary arteries and aortic rings respectively. Calculated remaining stress values following acetylcholine (ACh) or sodium nitroprusside (SNP) withdrawal. Values expressed mean ± SEM n = 3–8