Fig. 1From: Copper oxide nanoparticle toxicity profiling using untargeted metabolomicsCharacterization of CuO NPs. Including (a) dissolution of 10 μg/ml CuO NPs (maximum potential Cu ion release = 8 μg/ml, and would be represented as 100 % dissolution), black entries represent Cu ions detected after incubation of CuO NPs in CCM for increasing lengths of time, green represents Cu ions detected in CCM alone, red represents CuCl2 control; b transmission electron microscopy (TEM) micrographs of CuO NPs, scale bars are shown at bottom right of each image; c size distribution histogram of CuO NP hydrodynamic diameter when suspended in water, determined by DLS; d size distribution histogram of CuO NP hydrodynamic diameter when suspended in CCM, determined by DLS; e size distribution histogram of CuO NP diameter, determined by TEMBack to article page