Fig. 3
From: Copper oxide nanoparticle toxicity profiling using untargeted metabolomics
Principal Component Analysis Score plots showing controls (C) and treated samples (T) for the different time points (0 h, 1 h, 3 h, 6 h, 12 h, 24 h) and the biological replicates independently (n = 3) as datasets 1, 2, and 3. a reversed-phase HPLC - & positive ionization (RP_pos): R2cum (0.591),Q2cum (0.481); b reversed-phase HPLC & negative ionization (RP_neg): R2cum (0.575),Q2cum (0.459); c HILIC & positive ionization (pos) (without T.1 h.1, T.24 h.1): R2cum (0.732),Q2cum (0.586); d HILIC & negative ionization (neg) (without T.24 h.1): R2cum (0.618),Q2cum (0.542)