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Fig. 5 | Particle and Fibre Toxicology

Fig. 5

From: Copper oxide nanoparticle toxicity profiling using untargeted metabolomics

Fig. 5

Glutathione redox state in response to CuO NPs. A549 cells treated with CuO NPs at 0, 2.5, 5.0, 10, 20 and 40 μg/ml for 1, 3, 6, 12 and 24 h. Data is expressed as GSH/GSSG ratio, and each data point represents the mean ± SEM (n = 4). Statistical significance (determined by ANOVA with Tukey posthoc) is shown by * = p < 0.05, ** = p < 0.01, *** = p < 0.005, when compared to medium only treated cells

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