Fig. 5
From: Copper oxide nanoparticle toxicity profiling using untargeted metabolomics
Glutathione redox state in response to CuO NPs. A549 cells treated with CuO NPs at 0, 2.5, 5.0, 10, 20 and 40 μg/ml for 1, 3, 6, 12 and 24 h. Data is expressed as GSH/GSSG ratio, and each data point represents the mean ± SEM (n = 4). Statistical significance (determined by ANOVA with Tukey posthoc) is shown by * = p < 0.05, ** = p < 0.01, *** = p < 0.005, when compared to medium only treated cells