TY - JOUR AU - Kasai, Tatsuya AU - Umeda, Yumi AU - Ohnishi, Makoto AU - Mine, Takashi AU - Kondo, Hitomi AU - Takeuchi, Tetsuya AU - Matsumoto, Michiharu AU - Fukushima, Shoji PY - 2016 DA - 2016/10/13 TI - Lung carcinogenicity of inhaled multi-walled carbon nanotube in rats JO - Particle and Fibre Toxicology SP - 53 VL - 13 IS - 1 AB - Multi-walled carbon nanotubes (MWCNTs) constitute one of the most promising types of nanomaterials in industry today. With their increasing use, the potential toxicity and carcinogenicity of MWCNT needs to be evaluated in bioassay studies using rodents. Since humans are mainly exposed to MWCNT by inhalation, we performed a 104-week carcinogenicity study using whole-body inhalation exposure chambers with a fibrous straight type of MWCNT at concentrations of 0, 0.02, 0.2, and 2 mg/m3 using male and female F344 rats. SN - 1743-8977 UR - https://doi.org/10.1186/s12989-016-0164-2 DO - 10.1186/s12989-016-0164-2 ID - Kasai2016 ER -