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Table 2 Absolute and relative, body weights and lung weights in rats exposed to MWNT-7 for 104 weeks

From: Lung carcinogenicity of inhaled multi-walled carbon nanotube in rats

 

Male

Female

Group (mg/m3)

0

0.02

0.2

2

0

0.02

0.2

2

Numbers of animals examined

50

50

50

50

50

50

50

50

Survival animal number

36

42

38

37

42

34

39

36

  (rate:%)

(72)

(84)

(76)

(74)

(84)

(68)

(78)

(72)

Body weight

 Terminal body weight (g) mean

401

394

410

399

278

265

277

261 *

  SD

45

37

39

38

31

26

23

26

 Relative body weight (%) mean

100

98

102

100

100

95

100

94

Lung weight

 Terminal lung weight (g) mean

1.31

1.34

1.51 **

2.37 **

0.90

0.94 **

1.14 **

1.87 **

  SD

0.10

0.12

0.13

0.31

0.21

0.10

0.27

0.18

 Relative lung weight (%) mean

0.36

0.37

0.40 **

0.65 **

0.35

0.38 **

0.45 **

0.79 **

  SD

0.06

0.05

0.06

0.20

0.10

0.05

0.14

0.16

  1. Terminal body weight (g): Absolute body weight at the end of 104 weeks
  2. Relative body weight (%): Percentage of the body weight in the control group
  3. Terminal lung weight (g): Absolute lung weight at the end of 104 weeks
  4. Relative lung weight (%): Percentage of the terminal lung weight in each animal’s body weight
  5. Significant difference; *: p≦0.05 **: p≦0.01 by Dunnett’s Test
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Particle and Fibre Toxicology

ISSN: 1743-8977

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