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Table 1 Physiochemical characterization

From: Comparative toxicity and biodistribution assessments in rats following subchronic oral exposure to copper nanoparticles and microparticles

Items

Cu NPs

Cu MPs

Shape

Spherical

Spherical

Primary sizea

32.7 ± 10.5 nm

25.3 ± 6.6 μm

Hydrodynamic size (nm)b

pH 1.5

n.a

n.a

pH 6.5

516 ± 116.9

n.a

pH 7.8

334 ± 128.3

n.a

Surface area (m2/g)c

14.7

0.16

Zeta potential (mV)d

pH 1.5

25.5 ± 0.8

n.a

pH 6.5

1.32 ± 1.2

n.a

pH 7.8

−6.2 ± 0.2

n.a

  1. Note
  2. aPrimary size of Cu NPs and Cu MPs was measured by transmission electron microscopy (300 counts and 100 counts, respectively)
  3. bHydrodynamic size of Cu NPs was measured by a dynamic light scattering method
  4. cSurface area was measured by the Brunauer-Emmett-Teller method (N2 gas)
  5. dZeta potential was measured using electrophoretic light scattering method under pH 1.5, pH 6.5 and pH 7.8 conditions
  6. n.a. not available
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Particle and Fibre Toxicology

ISSN: 1743-8977

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