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Table 6 LOAELs in μg/cm2 determined with the cytotoxity and oxidative stress effects for each exposure method used

From: Air-liquid interface exposure to aerosols of poorly soluble nanomaterials induces different biological activation levels compared to exposure to suspensions

  Alamar blue LDH DCFDA
  ALIa Subm insertb Subm platec ALIa Subm insertb Subm platec ALIa Subm insertb Subm platec
NM105 1 10 3 1 3 10 Ø 10 10
NM101 Ø Ø 20 Ø 3 10 1 Ø Ø
NM100 Ø Ø Ø Ø 10 Ø Ø 10 Ø
NM212 Ø 10 10 Ø 10 Ø Ø Ø Ø
  1. aExposure at the air-liquid interface in inserts (ALI)
  2. bExposure in submerged conditions in inserts
  3. cExposure in submerged conditions in plates
  4. Ø No effects measured at tested doses