Skip to main content


Fig. 3 | Particle and Fibre Toxicology

Fig. 3

From: Contrasting biological potency of particulate matter collected at sites impacted by distinct industrial sources

Fig. 3

Cytotoxic potency of size-fractionated particles from industrial sites. Cytotoxic potency (β) was estimated using the slope of the dose-effect relationship from n = 3 independent experiments as described in the Methods section. Potency was assessed according to resazurin reduction and lactate dehydrogenase (LDH) release in J774A.1 macrophage-like cells (a, b) and A549 epithelial-like cells (c, d) respectively. For both assays, the height of the bar represents the potency, with greater negative numbers in the resazurin reduction assay and greater positive numbers in the LDH release assay corresponding to increased potency. HB, Hamilton Beach steel mill; MA, Montréal petrochemical refinery; MC, Montréal copper smelter; SR, Sarnia petrochemical refinery; SW, Shawinigan aluminum smelter

Back to article page