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Fig. 6 | Particle and Fibre Toxicology

Fig. 6

From: Surface area-dependence of gas-particle interactions influences pulmonary and neuroinflammatory outcomes

Fig. 6

Cytokine protein expression profile in bronchial lavage fluid after acute (1-day) exposure to atmospheres. After 1-day of exposure to the atmospheres, bronchial lavage fluid (BALF) was obtained from animals and assessed for cytokine protein expression for (a) TNF-α in C57BL/76 BALF, (b) IFN-γ in C57BL/6 BALF, (c) TNF-α in ApoE−/− BALF, and (d) IFN-γ in ApoE−/− BALF. No change in (a) TNF-α expression was observed in C57BL/6 animals, while (b) IFN-γ expression was significantly reduced in the UFP + G exposure group in the same animals. In ApoE−/− animals, (c) TNF-α protein expression was increased in the UFP and UFP + G groups with (d) no significant change in IFN- γ expression. n = 7–8 per group, *p < .05; **p < .01; ***p < .001; ****p < .0001

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