Fig. 7

Cytokine protein expression profile in bronchial lavage fluid after chronic (30-day) exposure to atmospheres. After 30-days of exposure to the atmospheres, bronchial lavage fluid (BALF) was obtained from animals and assessed for cytokine protein expression for the (a) CXCL1 in C57BL/6 BALF, (b) TNF-α in C57BL/6 BALF, (c) CXCL1 in ApoE^−/− BALF and (d) TNF-α in ApoE^−/− BALF. The most significant changes were induced by exposure to UFP + G: (a) CXCL1 expression in C57BL/6 animals, (b) TNF-α expression in C57BL/6 animals, (c) CXCL1 expression in ApoE^−/− animals, and (d) TNF-α expression in ApoE^−/− were all significantly increased in after chronic exposure to UFP + G. (e) CXCL1 expression was significantly increased in C57BL/6 animals in response to UFP + G compared to ApoE^−/− animals. n = 7–8 per group, *p < .05; **p < .01; ***p < .001; ****p < .0001