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Table 6 One-way ANOVA statistical analysis of qPCR gene expression in hippocampus

From: Surface area-dependence of gas-particle interactions influences pulmonary and neuroinflammatory outcomes

Strain Exposure Gene F-value P-value Posthoc analysis relative to control
C57BL/6 Acute Ccl5 F(4,32) = 5.808 p < .0012 UFP
C57BL/6 Acute Cxcl1 F(4,27) = 8.175 p < .0001 UFP
C57BL/6 Acute IL-1β F(4,32) = 3.404 p = 0.0199 UFP + G, FP + G
C57BL/6 Acute IL-6 F(4,33) = 52.50 p < .0001 UFP + G, FP, FP + G (decreased)
C57BL/6 Acute Tgf-β F(4,33) = 27.02 p < .0001 UFP (increased), UFP + G, FP, FP + G (decreased)
C57BL/6 Acute Tnf-α F(4,33) = 3.909 p = .0105 UFP
C57BL/6 Acute Vcam-1 F(4,32) = 1.205 ns none
ApoE−/− Acute Ccl5 F(4,30) = 0.2138 ns none
ApoE−/− Acute Cxcl1 F(4,30) = 4.377 p = 0.0066 none
ApoE−/− Acute IL-1β F(4,29) = 2.766 p = 0.05 UFP, UFP + G
ApoE−/− Acute IL-6 F(4,31) = 6.408 p < 0.001 UFP, UFP + G, FP
ApoE−/− Acute Tgf-β F(4,31) = 3.978 p = .0102 UFP, FP
ApoE−/− Acute Tnf-α F(4,30) = 4.556 p = .0054 UFP, UFP + G, FP, FP + G
ApoE−/− Acute Vcam-1 F(4,30) = 8.388 p < .0001 FP
C57BL/6 Chronic Ccl5 F(4,19) = 2.967 p = .0448 UFP
C57BL/6 Chronic Ccl2 F(4,18) = 1.398 ns none
C57BL/6 Chronic Cxcl1 F(4,19) = 1.132 ns none
C57BL/6 Chronic Et1 F(4,19) = 1.866 ns none
C57BL/6 Chronic IL-6 F(4,19) = 2.789 ns (p = .0560) none
C57BL/6 Chronic Tgf-β F(4,19) = 2.930 p = .0452 UFP + G, FP
C57BL/6 Chronic Vcam-1 F(4,19) = 2.962 p = .0465 UFP + G, FP
ApoE−/− Chronic Ccl5 F(4,32) = 3.248 p = .0241 UFP + G
ApoE−/− Chronic Ccl2 F(4,29) = 1.422 ns none
ApoE−/− Chronic Cxcl1 F(4,27) = 12.02 p < .0001 UFP, UFP + G
ApoE−/− Chronic Et1 F(4,32) = 1.78 ns none
ApoE−/− Chronic IL-6 F(4,32) = 16.45 p < .0001 UFP, UFP + G
ApoE−/− Chronic Tgf-β F(4,32) = 27.87 p < .0001 UFP, UFP + G
ApoE−/− Chronic Vcam-1 F(4,29) = 3.416 p = .0209 none