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Fig. 4 | Particle and Fibre Toxicology

Fig. 4

From: Nanoparticle exposure reactivates latent herpesvirus and restores a signature of acute infection

Fig. 4

Immunohistochemical staining shows increased expression of lytic viral proteins in lungs persistently infected with MHV-68 and subsequently exposed to NP: Lung sections were stained with a rabbit-polyclonal serum directed against lytic proteins of MHV-68. Arrows indicate positive staining in the positive control a and in latently infected mice treated subsequently with NP c and d. No positive staining was detected in mice with latent virus only b. Scale bar: 200 μm. Representative stainings from 3 mice per group are shown

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