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Fig. 3 | Particle and Fibre Toxicology

Fig. 3

From: Reduction of pulmonary toxicity of metal oxide nanoparticles by phosphonate-based surface passivation

Fig. 3

Safe design of MOx by surface passivation. a Formation of EDTMP-metal conjugate on MOx surface, b Ion release and oxidative capability of uncoated and EDTMP coated MOx, and c Comparison of ROS generation and cell viabilities in BEAS-2B cells exposed to uncoated and EDTMP coated MOx. The measurement of ion release and oxidative capability was described in the legend of Fig. 1. After 16 h exposure of BEAS-2B cells to 100 μg/mL MO suspensions, intracellular ROS generation was visualized by Mitosox staining. The cell viabilities were determined by MTS assay in BEAS-2B cells after 24 h incubation with 200 μg/mL MO suspensions. * p < 0.05 compared to uncoated MOx

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Particle and Fibre Toxicology

ISSN: 1743-8977

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