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Fig. 2 | Particle and Fibre Toxicology

Fig. 2

From: Osteopontin enhances multi-walled carbon nanotube-triggered lung fibrosis by promoting TGF-β1 activation and myofibroblast differentiation

Fig. 2

Induced secretion of OPN in the BAL. (a) Time course study. WT mice were treated with DM or MWCNTs (40 μg) for 1, 3, 7, 14, 28, and 56 days. The OPN level in BAL fluid was determined by ELISA (mean ± SD, n = 5). (b) Dose dependence study. WT mice were treated with DM or MWCNTs (5, 20, or 40 μg) for 7 days. The OPN level in BAL fluid was determined by ELISA (mean ± SD, n = 5)

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