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Fig. 2 | Particle and Fibre Toxicology

Fig. 2

From: Early pulmonary response is critical for extra-pulmonary carbon nanoparticle mediated effects: comparison of inhalation versus intra-arterial infusion exposures in mice

Fig. 2

Heatmap representation of lung transcript and protein panel assays following inhalation and intra-arterial infusion exposure of carbon nanoparticles (CNP). a. Transcript expression levels of 59 genes representing epithelial/endothelial activation, inflammatory cell markers, inflammation mediators and oxidative stress are shown. b. Protein expression levels of 34 markers representing epithelial/endothelial activation, inflammatory cell markers, inflammation mediators are shown. Samples were pooled from 4 animals/experimental group for transcript and protein analysis. Expression values are provided as percentage relative to time matched control. Fold changes below 1.5 were considered insignificant and are indicated in black color. IHA: inhalation; IAI: intra-arterial infusion

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