Fig. 4
From: Programming of mouse obesity by maternal exposure to concentrated ambient fine particles
Maternal exposure to CAP increases sensitivity to exogenous leptin but decreases central leptin signaling. a the food intake response of male offspring to leptin (i.p., 3 mg/kg). nFA = 7 and nCAP = 7. *p < 0.05, two way ANOVA. b the change of food intake in male offspring after leptin treatment (i.p., 3 mg/kg). nFA = 7 and nCAP = 7. *p < 0.05, two way ANOVA. c the change of body weight in male offspring after leptin treatment (i.p., 3 mg/kg). nFA = 7 and nCAP = 7. d the food intake response of female offspring to leptin (i.p., 3 mg/kg). nFA = 6 and nCAP = 6. e the change of food intake in female offspring after leptin treatment (i.p., 3 mg/kg). nFA = 6 and nCAP = 6. f the change of body weight in female offspring after leptin treatment (i.p., 3 mg/kg). nFA = 6 and nCAP = 6. g-p, the mRNA expression levels of denoted genes in hypothalamus were determined by qPCR. nMale/FA = 6, nMale/CAP = 7, nFemale/FA = 4, and nFemale/CAP = 7. *p < 0.05, one way ANOVA