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Fig. 5 | Particle and Fibre Toxicology

Fig. 5

From: Programming of mouse obesity by maternal exposure to concentrated ambient fine particles

Fig. 5

Maternal exposure to CAP decreases adipose leptin expression. a the plasma leptin levels of adult offspring. nMale/FA = 6, nMale/CAP = 7, nFemale/FA = 4, and nFemale/CAP = 7. *p < 0.05, one way ANOVA. b the plasma adiponectin levels of adult offspring. nMale/FA = 6, nMale/CAP = 7, nFemale/FA = 4, and nFemale/CAP = 7. *p < 0.05, one way ANOVA. c the mRNA expression levels of offspring epididymal adipose tissues. nMale/FA = 6, nMale/CAP = 7, nFemale/FA = 4, and nFemale/CAP = 7. *p < 0.05, one way ANOVA. d the representative image of western blot analysis of leptin protein in epididymal adipose tissues. e the quantification of leptin protein in epididymal adipose tissues. nMale/FA = 6, nMale/CAP = 7, nFemale/FA = 4, and nFemale/CAP = 7. *p < 0.05, one way ANOVA. f the average methylation level of leptin promoter in adipocytes. nMale/FA = 6, nMale/CAP = 7, nFemale/FA = 4, and nFemale/CAP = 7. *p < 0.05, one way ANOVA

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