| Lung burden (μg/lung ± SD) | Clearance t1/2 (days) | ||||
---|---|---|---|---|---|---|
d 1 | d 28 | d 90Â +Â 1rec | d 90Â +Â 28rec | d 90Â +Â 90rec | ||
Clean air | 1.2 ± 1.0 | 0.6 ± 0.2 | 1.8 ± 0.8 | 0.8 ± 0.5 | 1.3 ± 1.3 | - |
0.1 mg/m3 CeO2 | 2.5 ± 0.8 | 12.0 ± 2.9 | 33.1 ± 1.4 | 24.7 ± 6.1 | 13.2 ± 3.2 | 67 |
0.3 mg/m3 CeO2 | 5.4 ± 1.9 | 33.5 ± 2.8 | 99.2 ± 10.1 | 85.1 ± 18.2 | 41.9 ± 8.8 | 69 |
1.0 mg/m3 CeO2 | 19.6 ± 5.6 | 152 ± 37.4 | 476 ± 74.0 | 366 ± 24.7 | 263 ± 15.4 | 108 |
3.0 mg/m3 CeO2 | 21.0 ± 1.0 | 391 ± 92.3 | 1280 ± 82.5 | 1285 ± 69.9 | 1013 ± 243 | 224 |
50.0 mg/m3 BaSO4 | 143 ± 16.3 | 1078 ± 197 | 1591 ± 530 | 871 ± 322 | 571 ± 358 | 56 |