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Fig. 8 | Particle and Fibre Toxicology

Fig. 8

From: STAT1-dependent and -independent pulmonary allergic and fibrogenic responses in mice after exposure to tangled versus rod-like multi-walled carbon nanotubes

Fig. 8

TGF-β1 protein levels and p-Smad2/3 levels in lung tissue from Stat1 +/+ and Stat1 −/− mice after 21 days of exposure to tMWCNTs or rMWCNTs. a TGF-β1 protein in BALF was measured by ELISA (***p < 0.001 compared to controls; *p < 0.05 between genotypes). b Representative Western blot showing p-Smad2/3 and total Smad2/3 protein levels in lung tissue. c Densitometry of total Smad2/3 levels normalized to β-actin levels. d Quantification of the ratio of p-Smad2/3 to total Smad2/3 densitometry levels relative to β-actin

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