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Fig. 4 | Particle and Fibre Toxicology

Fig. 4

From: Multi-walled carbon nanotubes-induced alterations in microRNA let-7 and its targets activate a protection mechanism by conferring a developmental timing control

Fig. 4

Genetic interaction between let-7 and hbl-1 or lin-41 in the regulation of MWCNTs toxicity. a Genetic interaction between let-7 and hbl-1 or lin-41 in the regulation of MWCNTs toxicity in inducing intestinal ROS production. Sixty nematodes were examined per treatment. b Genetic interaction between let-7 and hbl-1 or lin-41 in the regulation of MWCNTs toxicity in decreasing locomotion behavior. Sixty nematodes were examined per treatment. Prolonged exposure was performed from L1-larvae to young adults. Exposure concentration of MWCNTs was 10 μg/L. Bars represent means ± SD. ** P < 0.01 vs wild-type (if not specially indicated)

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