Fig. 8

Impact of CuO NP, CuO MP and CuCl2 on Nrf2 activity. HeLa S3 cells were treated for 5 h with the different copper compounds. Shown are mean values of three independent experiments + SD. Statistically significant different from control: ***p ≤ 0.001 (ANOVA-Dunnett’s T test). 20 μg/mL CuO are equal to 252 μM Cu2+