Fig. 8From: Comparison between micro- and nanosized copper oxide and water soluble copper chloride: interrelationship between intracellular copper concentrations, oxidative stress and DNA damage response in human lung cellsImpact of CuO NP, CuO MP and CuCl2 on Nrf2 activity. HeLa S3 cells were treated for 5 h with the different copper compounds. Shown are mean values of three independent experiments + SD. Statistically significant different from control: ***p ≤ 0.001 (ANOVA-Dunnett’s T test). 20 μg/mL CuO are equal to 252 μM Cu2+ Back to article page